PhytophthoraV1, Main, Exploration, bibRecord, 000958

Nicotiana benthamiana Matrix Metalloprotease 1 (NMMP1) gene confers disease resistance to Phytophthora infestans in tobacco and potato plants.

Identifieur interne : 000958 ( Main/Exploration ); précédent : 000957; suivant : 000959

Nicotiana benthamiana Matrix Metalloprotease 1 (NMMP1) gene confers disease resistance to Phytophthora infestans in tobacco and potato plants.

Auteurs : Jang Ho Ha [Corée du Sud] ; Hyun A. Jang [Corée du Sud] ; Ki-Beom Moon [Corée du Sud] ; Kwang Hyun Baek [Corée du Sud] ; Gyung Ja Choi [Corée du Sud] ; Doil Choi [Corée du Sud] ; Hye Sun Cho [Corée du Sud] ; Suk Yun Kwon [Corée du Sud] ; Jae-Heung Jeon [Corée du Sud] ; Sang-Keun Oh [Corée du Sud] ; Hyun-Soon Kim [Corée du Sud]

Source :

Journal of plant physiology [ 1618-1328 ] ; 2017.

RBID : pubmed:28888160

Descripteurs français

English descriptors

KwdEn :
- Disease Resistance (MeSH), Matrix Metalloproteinase 1 (genetics), Matrix Metalloproteinase 1 (immunology), Phytophthora infestans (physiology), Plant Diseases (genetics), Plant Diseases (immunology), Plant Diseases (microbiology), Plant Proteins (genetics), Plant Proteins (immunology), Plants, Genetically Modified (genetics), Plants, Genetically Modified (immunology), Plants, Genetically Modified (microbiology), Solanum tuberosum (genetics), Solanum tuberosum (immunology), Solanum tuberosum (microbiology), Tobacco (genetics), Tobacco (immunology), Tobacco (microbiology), Up-Regulation (MeSH).
MESH :
- chemical , genetics : Matrix Metalloproteinase 1, Plant Proteins.
- chemical , immunology : Matrix Metalloproteinase 1, Plant Proteins.
- genetics : Plant Diseases, Plants, Genetically Modified, Solanum tuberosum, Tobacco.
- immunology : Plant Diseases, Plants, Genetically Modified, Solanum tuberosum, Tobacco.
- microbiology : Plant Diseases, Plants, Genetically Modified, Solanum tuberosum, Tobacco.
- physiology : Phytophthora infestans.
- Disease Resistance, Up-Regulation.

Abstract

We previously isolated Nicotiana benthamiana matrix metalloprotease 1 (NMMP1) from tobacco leaves. The NMMP1 gene encodes a highly conserved, Zn-containing catalytic protease domain that functions as a factor in the plant's defense against bacterial pathogens. Expression of NMMP1 was strongly induced during interactions between tobacco and one of its pathogens, Phytophthora infestans. To elucidate the role of the NMMP1 in defense of N. benthamiana against fungal pathogens, we performed gain-of-function and loss-of-function studies. NMMP1-overexpressing plants had stronger resistance responses against P. infestans infections than control plants, while silencing of NMMP1 resulted in greater susceptibility of the plants to the pathogen. This greater susceptibility correlated with fewer NMMP1 transcripts than the non-silenced control. We also examined cell death as a measure of disease. The amount of cell death induced by the necrosis-inducing P. infestans protein 1, PiNPP1, was dependent on NMMP1 in N. benthamiana. Potato plants overexpressing NMMP1 also had enhanced disease resistance against P. infestans. RT-PCR analysis of these transgenic potato plants revealed constitutive up-regulation of the potato defense gene NbPR5. NMMP1-overexpressing potato plants were taller and produced heavier tubers than control plants. We suggest a role for NMMP1in pathogen defense and development.

DOI: 10.1016/j.jplph.2017.08.010
PubMed: 28888160

Affiliations:

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Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Disease Resistance (MeSH)</term>
<term>Matrix Metalloproteinase 1 (genetics)</term>
<term>Matrix Metalloproteinase 1 (immunology)</term>
<term>Phytophthora infestans (physiology)</term>
<term>Plant Diseases (genetics)</term>
<term>Plant Diseases (immunology)</term>
<term>Plant Diseases (microbiology)</term>
<term>Plant Proteins (genetics)</term>
<term>Plant Proteins (immunology)</term>
<term>Plants, Genetically Modified (genetics)</term>
<term>Plants, Genetically Modified (immunology)</term>
<term>Plants, Genetically Modified (microbiology)</term>
<term>Solanum tuberosum (genetics)</term>
<term>Solanum tuberosum (immunology)</term>
<term>Solanum tuberosum (microbiology)</term>
<term>Tobacco (genetics)</term>
<term>Tobacco (immunology)</term>
<term>Tobacco (microbiology)</term>
<term>Up-Regulation (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Maladies des plantes (génétique)</term>
<term>Maladies des plantes (immunologie)</term>
<term>Maladies des plantes (microbiologie)</term>
<term>Matrix metalloproteinase 1 (génétique)</term>
<term>Matrix metalloproteinase 1 (immunologie)</term>
<term>Phytophthora infestans (physiologie)</term>
<term>Protéines végétales (génétique)</term>
<term>Protéines végétales (immunologie)</term>
<term>Régulation positive (MeSH)</term>
<term>Résistance à la maladie (MeSH)</term>
<term>Solanum tuberosum (génétique)</term>
<term>Solanum tuberosum (immunologie)</term>
<term>Solanum tuberosum (microbiologie)</term>
<term>Tabac (génétique)</term>
<term>Tabac (immunologie)</term>
<term>Tabac (microbiologie)</term>
<term>Végétaux génétiquement modifiés (génétique)</term>
<term>Végétaux génétiquement modifiés (immunologie)</term>
<term>Végétaux génétiquement modifiés (microbiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Matrix Metalloproteinase 1</term>
<term>Plant Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Matrix Metalloproteinase 1</term>
<term>Plant Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Plant Diseases</term>
<term>Plants, Genetically Modified</term>
<term>Solanum tuberosum</term>
<term>Tobacco</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Maladies des plantes</term>
<term>Matrix metalloproteinase 1</term>
<term>Protéines végétales</term>
<term>Solanum tuberosum</term>
<term>Tabac</term>
<term>Végétaux génétiquement modifiés</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Maladies des plantes</term>
<term>Matrix metalloproteinase 1</term>
<term>Protéines végétales</term>
<term>Solanum tuberosum</term>
<term>Tabac</term>
<term>Végétaux génétiquement modifiés</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Plant Diseases</term>
<term>Plants, Genetically Modified</term>
<term>Solanum tuberosum</term>
<term>Tobacco</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Maladies des plantes</term>
<term>Solanum tuberosum</term>
<term>Tabac</term>
<term>Végétaux génétiquement modifiés</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Plant Diseases</term>
<term>Plants, Genetically Modified</term>
<term>Solanum tuberosum</term>
<term>Tobacco</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Phytophthora infestans</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Phytophthora infestans</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Disease Resistance</term>
<term>Up-Regulation</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Régulation positive</term>
<term>Résistance à la maladie</term>
</keywords>
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<front><div type="abstract" xml:lang="en">We previously isolated Nicotiana benthamiana matrix metalloprotease 1 (NMMP1) from tobacco leaves. The NMMP1 gene encodes a highly conserved, Zn-containing catalytic protease domain that functions as a factor in the plant's defense against bacterial pathogens. Expression of NMMP1 was strongly induced during interactions between tobacco and one of its pathogens, Phytophthora infestans. To elucidate the role of the NMMP1 in defense of N. benthamiana against fungal pathogens, we performed gain-of-function and loss-of-function studies. NMMP1-overexpressing plants had stronger resistance responses against P. infestans infections than control plants, while silencing of NMMP1 resulted in greater susceptibility of the plants to the pathogen. This greater susceptibility correlated with fewer NMMP1 transcripts than the non-silenced control. We also examined cell death as a measure of disease. The amount of cell death induced by the necrosis-inducing P. infestans protein 1, PiNPP1, was dependent on NMMP1 in N. benthamiana. Potato plants overexpressing NMMP1 also had enhanced disease resistance against P. infestans. RT-PCR analysis of these transgenic potato plants revealed constitutive up-regulation of the potato defense gene NbPR5. NMMP1-overexpressing potato plants were taller and produced heavier tubers than control plants. We suggest a role for NMMP1in pathogen defense and development.</div>
</front>
</TEI>
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<DateCompleted><Year>2018</Year>
<Month>05</Month>
<Day>14</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>09</Month>
<Day>30</Day>
</DateRevised>
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<PubDate><Year>2017</Year>
<Month>Nov</Month>
</PubDate>
</JournalIssue>
<Title>Journal of plant physiology</Title>
<ISOAbbreviation>J Plant Physiol</ISOAbbreviation>
</Journal>
<ArticleTitle>Nicotiana benthamiana Matrix Metalloprotease 1 (NMMP1) gene confers disease resistance to Phytophthora infestans in tobacco and potato plants.</ArticleTitle>
<Pagination><MedlinePgn>189-195</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jplph.2017.08.010</ELocationID>
<Abstract><AbstractText>We previously isolated Nicotiana benthamiana matrix metalloprotease 1 (NMMP1) from tobacco leaves. The NMMP1 gene encodes a highly conserved, Zn-containing catalytic protease domain that functions as a factor in the plant's defense against bacterial pathogens. Expression of NMMP1 was strongly induced during interactions between tobacco and one of its pathogens, Phytophthora infestans. To elucidate the role of the NMMP1 in defense of N. benthamiana against fungal pathogens, we performed gain-of-function and loss-of-function studies. NMMP1-overexpressing plants had stronger resistance responses against P. infestans infections than control plants, while silencing of NMMP1 resulted in greater susceptibility of the plants to the pathogen. This greater susceptibility correlated with fewer NMMP1 transcripts than the non-silenced control. We also examined cell death as a measure of disease. The amount of cell death induced by the necrosis-inducing P. infestans protein 1, PiNPP1, was dependent on NMMP1 in N. benthamiana. Potato plants overexpressing NMMP1 also had enhanced disease resistance against P. infestans. RT-PCR analysis of these transgenic potato plants revealed constitutive up-regulation of the potato defense gene NbPR5. NMMP1-overexpressing potato plants were taller and produced heavier tubers than control plants. We suggest a role for NMMP1in pathogen defense and development.</AbstractText>
<CopyrightInformation>Copyright © 2017 Elsevier GmbH. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ha</LastName>
<ForeName>Jang Ho</ForeName>
<Initials>JH</Initials>
<AffiliationInfo><Affiliation>Plant Systems Engineering Research Center, KRIBB, Yusung, Daejeon, 34141, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jang</LastName>
<ForeName>Hyun A</ForeName>
<Initials>HA</Initials>
<AffiliationInfo><Affiliation>Department of Applied Biology CALS, Chungnam National University, Deajeon, 34134, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Moon</LastName>
<ForeName>Ki-Beom</ForeName>
<Initials>KB</Initials>
<AffiliationInfo><Affiliation>Plant Systems Engineering Research Center, KRIBB, Yusung, Daejeon, 34141, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Baek</LastName>
<ForeName>Kwang Hyun</ForeName>
<Initials>KH</Initials>
<AffiliationInfo><Affiliation>School of Biotechnology, Yeungnam University, Gyeongsan, 38541, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Choi</LastName>
<ForeName>Gyung Ja</ForeName>
<Initials>GJ</Initials>
<AffiliationInfo><Affiliation>Center for Eco-friendly New Materials, KRICT, Daejeon, 34114, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Choi</LastName>
<ForeName>Doil</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Plant Sciences, Seoul National University, Seoul, 08826, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cho</LastName>
<ForeName>Hye Sun</ForeName>
<Initials>HS</Initials>
<AffiliationInfo><Affiliation>Plant Systems Engineering Research Center, KRIBB, Yusung, Daejeon, 34141, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kwon</LastName>
<ForeName>Suk Yun</ForeName>
<Initials>SY</Initials>
<AffiliationInfo><Affiliation>Plant Systems Engineering Research Center, KRIBB, Yusung, Daejeon, 34141, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jeon</LastName>
<ForeName>Jae-Heung</ForeName>
<Initials>JH</Initials>
<AffiliationInfo><Affiliation>Plant Systems Engineering Research Center, KRIBB, Yusung, Daejeon, 34141, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Oh</LastName>
<ForeName>Sang-Keun</ForeName>
<Initials>SK</Initials>
<AffiliationInfo><Affiliation>Department of Applied Biology CALS, Chungnam National University, Deajeon, 34134, Republic of Korea. Electronic address: sangkeun@cnu.ac.kr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kim</LastName>
<ForeName>Hyun-Soon</ForeName>
<Initials>HS</Initials>
<AffiliationInfo><Affiliation>Plant Systems Engineering Research Center, KRIBB, Yusung, Daejeon, 34141, Republic of Korea. Electronic address: hyuns@kribb.re.kr.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>09</Month>
<Day>01</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Germany</Country>
<MedlineTA>J Plant Physiol</MedlineTA>
<NlmUniqueID>9882059</NlmUniqueID>
<ISSNLinking>0176-1617</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D010940">Plant Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.24.7</RegistryNumber>
<NameOfSubstance UI="D020781">Matrix Metalloproteinase 1</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D060467" MajorTopicYN="Y">Disease Resistance</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020781" MajorTopicYN="N">Matrix Metalloproteinase 1</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055750" MajorTopicYN="N">Phytophthora infestans</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010935" MajorTopicYN="N">Plant Diseases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010940" MajorTopicYN="N">Plant Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D030821" MajorTopicYN="N">Plants, Genetically Modified</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011198" MajorTopicYN="N">Solanum tuberosum</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014026" MajorTopicYN="N">Tobacco</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015854" MajorTopicYN="N">Up-Regulation</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Matrix metalloprotease</Keyword>
<Keyword MajorTopicYN="N">Phytophthora infestans</Keyword>
<Keyword MajorTopicYN="N">Resistance responses</Keyword>
<Keyword MajorTopicYN="N">Transgenic plants</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year>
<Month>05</Month>
<Day>22</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2017</Year>
<Month>08</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2017</Year>
<Month>08</Month>
<Day>28</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>9</Month>
<Day>10</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2018</Year>
<Month>5</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
<Month>9</Month>
<Day>10</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">28888160</ArticleId>
<ArticleId IdType="pii">S0176-1617(17)30229-8</ArticleId>
<ArticleId IdType="doi">10.1016/j.jplph.2017.08.010</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Corée du Sud</li>
</country>
<settlement><li>Séoul</li>
</settlement>
<orgName><li>Université nationale de Séoul</li>
</orgName>
</list>
<tree><country name="Corée du Sud"><noRegion><name sortKey="Ha, Jang Ho" sort="Ha, Jang Ho" uniqKey="Ha J" first="Jang Ho" last="Ha">Jang Ho Ha</name>
</noRegion>
<name sortKey="Baek, Kwang Hyun" sort="Baek, Kwang Hyun" uniqKey="Baek K" first="Kwang Hyun" last="Baek">Kwang Hyun Baek</name>
<name sortKey="Cho, Hye Sun" sort="Cho, Hye Sun" uniqKey="Cho H" first="Hye Sun" last="Cho">Hye Sun Cho</name>
<name sortKey="Choi, Doil" sort="Choi, Doil" uniqKey="Choi D" first="Doil" last="Choi">Doil Choi</name>
<name sortKey="Choi, Gyung Ja" sort="Choi, Gyung Ja" uniqKey="Choi G" first="Gyung Ja" last="Choi">Gyung Ja Choi</name>
<name sortKey="Jang, Hyun A" sort="Jang, Hyun A" uniqKey="Jang H" first="Hyun A" last="Jang">Hyun A. Jang</name>
<name sortKey="Jeon, Jae Heung" sort="Jeon, Jae Heung" uniqKey="Jeon J" first="Jae-Heung" last="Jeon">Jae-Heung Jeon</name>
<name sortKey="Kim, Hyun Soon" sort="Kim, Hyun Soon" uniqKey="Kim H" first="Hyun-Soon" last="Kim">Hyun-Soon Kim</name>
<name sortKey="Kwon, Suk Yun" sort="Kwon, Suk Yun" uniqKey="Kwon S" first="Suk Yun" last="Kwon">Suk Yun Kwon</name>
<name sortKey="Moon, Ki Beom" sort="Moon, Ki Beom" uniqKey="Moon K" first="Ki-Beom" last="Moon">Ki-Beom Moon</name>
<name sortKey="Oh, Sang Keun" sort="Oh, Sang Keun" uniqKey="Oh S" first="Sang-Keun" last="Oh">Sang-Keun Oh</name>
</country>
</tree>
</affiliations>
</record>

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Nicotiana benthamiana Matrix Metalloprotease 1 (NMMP1) gene confers disease resistance to Phytophthora infestans in tobacco and potato plants.

Nicotiana benthamiana Matrix Metalloprotease 1 (NMMP1) gene confers disease resistance to Phytophthora infestans in tobacco and potato plants.

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